Archive for Dog Adrenal Health

The symptoms of Cushings disease in dogs are often mistaken for normal signs of canine aging. But in fact, such symptoms may surface due to a hyperactive adrenal gland.

Although this disease cannot be cured completely, timely and adequate treatment can result in a longer and higher quality of life for the suffering dog.

The medical term used for Cushings disease is hyperadrenocorticism. Since the symptoms of the disease mimic the symptoms of other common diseases, the condition is often misdiagnosed or ignored.

Symptoms -like an increase in urination with pale, diluted urine, obesity with a pot belly, lethargy and intolerance to exercise, excessive thirst, a thin skin or alopecia (hair loss) - need to be taken seriously and warrant a visit to the veterinarian.

The major cause of hyperadrenocorticism in dogs is an excess of corticosteroids. The production of corticosteroids is controlled by a complex system that involves the pituitary gland.

The ACTH hormone, produced by the pituitary gland, moves through the blood stream and signals the adrenal glands near the kidneys to produce corticosteroids. In a healthy dog, it is a self-balancing system. However, when a tumor develops in the pituitary or adrenal glands, or when excessive administration of corticosteroids occurs for another reason, the level of required corticosteroids is compromised. This leads to Cushings disease.


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What is Cushings Disease?

Cushing’s disease is also known as hyperadrenocorticism and is characterized by the over-production of hormones from the adrenal glands. The extra high levels of these hormones in your pet’s body can cause varied and serious symptoms.

Function and definition of the adrenal glands

The adrenal glands are two, small bean-shaped structures situated above each of your pet’s two kidneys. They consist of two separate regions: an inner adrenal medulla surrounded by an outer adrenal cortex.

The adrenal glands release a wide variety of hormones. The medulla is responsible for producing epinephrine and norepinephrine (adrenaline). These hormones control the body’s reaction to stress and affect blood pressure and heart rate.

The adrenal cortex produces hormones such as cortisone and aldosterone which are necessary for balancing fluid and electrolytes (salt) in the body as well as regulating the use of dietary protein, fats and carbohydrates and controlling inflammation.

What are the symptoms of Cushings Disease?

High levels of corticosteroids in the body can cause a number of health problems in pets including:

* Increased thirst/drinking and urination
* Increased appetite
* Panting
* High blood pressure
* Loss of hair
* Calcified lumps in the skin
* Thinning skin and susceptibility to infections


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