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Feline Cushing’s Syndrome

By Tess Thompson

Cushing’s syndrome or hyperadrenocorticism is not as common in cats as it is among dogs. The treatments for Cushing’s disease in dogs is far more developed that those for cats. But that can hardly be reason for getting complacent since there have been a fair number of cases of feline hyperadrenocorticism that have been reported lately.

The best way to be prepared to tackle the syndrome is to understand the causes, symptoms, diagnosis and treatment. This helps in identifying the problem, confirming the presence and getting it treated effectively.

Causes

Cushing’s disease is a glandular disorder caused by excessive production of an adrenal-cortex hormone called cortisol.

A complex system of reciprocal interactions between the pituitary gland and the adrenal glands controls the cortisol levels in a cat’s body. An abnormal development like a tumor can disturb the fine balance of the amount of cortisol produced.

Sometimes, the condition can also be caused due to a high dosage of synthetic hormones that may have been used to treat other ailments.

Symptoms

* Excessive thirst and appetite.
* Loose and hanging abdomen.
* Hair loss resulting in a poor coat.
* Ear tip curling.
* Delicate and thin skin which is easily torn.
* Muscle weakness and lethargy.
* Uncontrolled diabetes.
* Increased urination.
* Diluted urine.

Diagnosis

The physical symptoms that accompany the condition are the first indication of Cushing’s disease. A presence and continuation of diabetes often leads to suspicion of Cushing’s disease. If the diabetes proves be difficult to control, it is almost a confirmation of the problem.

Routine laboratory tests are often inconclusive. A confirmed diagnosis requires a number of tests to establish the prevalence of the disease.

Once confirmed, further imaging tests like X-Rays, ultrasound examination and CT/MRI scan are conducted to assess whether the cause of the issue lies in the pituitary gland or the adrenal glands.


Treatment

If the Cushing’s disease has been caused by over-dosage of synthetic hormones, the hormones need to be stopped. A gradual reduction in the dosage is recommended since a complete stop can cause withdrawal symptoms.

Tumors in adrenal and pituitary glands are quite difficult to treat. Adrenal tumor can be removed by surgical excision. Tumors, in the pituitary glands are almost impossible to remove.

Hyperadrenocorticism in a dog is relatively more prevalent and that is probably one of the main reasons that not many drugs exist for Cushing’s disease in cats. The ones that do are also not effective enough to cure the condition completely.